Source:http://linkedlifedata.com/resource/pubmed/id/12481846
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-12-16
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pubmed:abstractText |
M cells are located in the epithelial layer covering the gut-associated lymphoid tissue and are responsible for delivery of macromolecules and microorganisms to the underlying lymphoid cells. It has been shown that the human colonic cell line Caco-2 can be converted to M cells in vitro following coculture with isolated lymphocytes from murine Peyer's patches. Studies were undertaken to evaluate and characterize the transepithelial transport of select macromolecules across these in vitro derived M cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1056-8719
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
93-101
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12481846-Animals,
pubmed-meshheading:12481846-Antigens,
pubmed-meshheading:12481846-Caco-2 Cells,
pubmed-meshheading:12481846-Epithelial Cells,
pubmed-meshheading:12481846-Female,
pubmed-meshheading:12481846-Humans,
pubmed-meshheading:12481846-Intestinal Mucosa,
pubmed-meshheading:12481846-Macromolecular Substances,
pubmed-meshheading:12481846-Mice,
pubmed-meshheading:12481846-Mice, Inbred BALB C,
pubmed-meshheading:12481846-Permeability,
pubmed-meshheading:12481846-Rats
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pubmed:articleTitle |
Permeability measurement of macromolecules and assessment of mucosal antigen sampling using in vitro converted M cells.
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pubmed:affiliation |
Pharmaceutics Department, Boehringer Ingelheim Pharmaceuticals, Inc., PO Box 368, 900 Ridgebury Road, Ridgefield, CT 06877, USA.
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pubmed:publicationType |
Journal Article
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