Linked Life Data

1247561

Source:http://linkedlifedata.com/resource/pubmed/id/1247561

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-4-9
pubmed:abstractText
The aim of this work is to describe quantitatively, from a physical point of view, molecular, molecular transport in thyroid slices. The study of the release of [3H]sucrose, [3H]inulin and 131I-labeled albumin leads to the following conclusions: the molecular transport in the slices is not due mainly to free diffusion. Indeed as these molecules are retained in the interfollicular spaces, the transport of matter is a mechanical process due to the agitation of the medium in which the slices are incubated. It depends on the elastic properties of the thyroid tissue, the frequency of the agitator and the thickness of the slice. This transport process can be described by a diffusion equation with an empirical diffusion coefficient; we call it diffusivity. These findings must be taken into account in any in vitro kinetic study of thyroid metabolism and of its regulation by effectors such as thyrotropin. The possibility of interference of such mechanical processes in the interpretation of kinetic tracer studies with tissue slices or fragments should be considered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
419
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
349-57
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Molecular transport in thyroid slices.
pubmed:publicationType
Journal Article, In Vitro