Linked Life Data

12474654

Source:http://linkedlifedata.com/resource/pubmed/id/12474654

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2002-12-6
pubmed:abstractText
The aim of the study was to evaluate and compare intensity and incidence of both, typical (heartburn, acid regurgitation) and atypical (hoarseness, throat clearing, globus pharyngeus) symptoms of laryngopharyngeal reflux disease among 72 patients and 123 healthy persons. Diagnosis of laryngopharyngeal reflux disease in 58 cases (80.6%) was confirmed by endoscopic and histological findings of esophagitis and in 14 cases (19.4%) by Omeprasol test. The intensity of the symptom was calculated by multiplication of the intensity and frequency of the symptom. According to the data obtained laryngopharyngeal reflux disease manifested more frequently with atypical symptoms. In the patients' group mean intensity of hoarseness was 5.29 +/- 0.74 points, mean index of hoarseness 7.06 +/- 1.35 points. Typical symptoms were found only in 14-22% of patients. The mean intensity of heartburn was 2.6 +/- 0.66 points, mean index of heartburn was 4.73 +/- 1.02 points. The incidence of atypical symptoms was three times higher than the incidence of typical symptoms (p < 0.05). According to the multinomial logistic regression analysis the combination of three atypical symptoms (hoarseness, throat clearing and globus pharyngeus) separated groups of the patients and healthy persons. The combination of these symptoms increases the odds ratio for laryngopharyngeal reflux disease 59.7 times. Idiopathic hoarseness as a single symptom increases the odds ratio for laryngopharyngeal reflux disease 85 times.
pubmed:language
lit
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1010-660X
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
699-705
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
[Typical and atypical symptoms of laryngopharyngeal reflux disease].
pubmed:affiliation
Kauno medicinos universiteto Ausu, nosies, gerkles ligu klinika, Eiveniu 2, 3007 Kaunas. ruta-prib@takas.lt
pubmed:publicationType
Journal Article, Comparative Study, English Abstract