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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0011155,
umls-concept:C0017337,
umls-concept:C0021469,
umls-concept:C0036341,
umls-concept:C0051334,
umls-concept:C0086860,
umls-concept:C0162429,
umls-concept:C0205419,
umls-concept:C0332285,
umls-concept:C1711351
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pubmed:issue |
12
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pubmed:dateCreated |
2002-12-9
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pubmed:abstractText |
The alpha7 neuronal nicotinic acetylcholine receptor subunit gene (CHRNA7) has been implicated as a candidate gene for schizophrenia, and for an auditory sensory processing deficit found in the disease, by both genetic linkage at 15q14 and biochemical data. The expression of CHRNA7 is reduced in several brain regions in schizophrenic subjects compared with control subjects. This study presents DNA sequence analysis of the core promoter region for CHRNA7 in schizophrenic and control subjects.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0003-990X
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pubmed:author |
pubmed-author:AdlerLawrence ELE,
pubmed-author:BergerRalphR,
pubmed-author:DrebingCarlaC,
pubmed-author:FreedmanRobertR,
pubmed-author:GaultJudithJ,
pubmed-author:HopkinsJanJ,
pubmed-author:LeonardSherryS,
pubmed-author:LogelJudithJ,
pubmed-author:OlincyAnnA,
pubmed-author:RossRandal GRG,
pubmed-author:ShortMargaretM,
pubmed-author:SirotaPinkhasP,
pubmed-author:VennDianaD,
pubmed-author:VianzonRubyR,
pubmed-author:ZerbeGaryG
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1085-96
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pubmed:dateRevised |
2010-6-4
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pubmed:meshHeading |
pubmed-meshheading:12470124-Auditory Perceptual Disorders,
pubmed-meshheading:12470124-Brain,
pubmed-meshheading:12470124-Chromosome Mapping,
pubmed-meshheading:12470124-Chromosomes, Human, Pair 15,
pubmed-meshheading:12470124-DNA Mutational Analysis,
pubmed-meshheading:12470124-Evoked Potentials, Auditory,
pubmed-meshheading:12470124-Genetic Variation,
pubmed-meshheading:12470124-Humans,
pubmed-meshheading:12470124-Lymphocytes,
pubmed-meshheading:12470124-Neural Inhibition,
pubmed-meshheading:12470124-Polymorphism, Genetic,
pubmed-meshheading:12470124-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:12470124-Promoter Regions, Genetic,
pubmed-meshheading:12470124-Receptors, Nicotinic,
pubmed-meshheading:12470124-Schizophrenia,
pubmed-meshheading:12470124-Schizophrenic Psychology,
pubmed-meshheading:12470124-Sequence Analysis, DNA
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pubmed:year |
2002
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pubmed:articleTitle |
Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia.
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pubmed:affiliation |
Department of Psychiatry, Campus Box C-268-71, University of Colorado Health Sciences Center, 4200 E Ninth Ave, Denver, CO 80262, USA. Sherry.Leonard@UCHSC.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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