Linked Life Data

12468003

Source:http://linkedlifedata.com/resource/pubmed/id/12468003

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-12-6
pubmed:abstractText
We developed the sliding window correlation procedure in order to examine populations for possible heterogeneity in the ways two variables are related with each other. This procedure involves computing correlation coefficients (R) for overlapping successive segments of the covariate scores. The distribution of resulting Rs reveals fluctuations in the degree and direction of R over the sample of ranked scores. This procedure is applied to behavioral data of aged rats, which were rank-ordered according to water maze performance, and correlated with open field exploration and conflict behavior in a light/dark chamber. Results revealed correlation coefficients of varying magnitudes and opposing directions for different segments of the population, which were obscured by overall correlation analysis. E.g. for the superior learners, the Rs were highest between maze learning ability, increased open field exploration and reduced anxiety in the conflict test, whereas for the intermediate learners the Rs were highest for maze learning ability related with reduced exploration and increased anxiety. Thus, the sliding window correlation distribution can be applied in conjunction with overall correlation analysis to provide information about the potential presence and locations of subgroups within a population, especially if overall correlation analysis does not yield significant results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0165-0270
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
121
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
129-37
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
The sliding window correlation procedure for detecting hidden correlations: existence of behavioral subgroups illustrated with aged rats.
pubmed:affiliation
Institute of Physiological Psychology, Center for Biological and Medical Research, University of Düsseldorf, Universitätstr. 1, D-40225 Düsseldorf, Germany.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't