Linked Life Data

12466461

Source:http://linkedlifedata.com/resource/pubmed/id/12466461

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2002-12-5
pubmed:abstractText
In many sensory systems, exposure to a prolonged stimulus causes adaptation, which tends to reduce neural responses to subsequent stimuli. Such effects are usually stimulus-specific, making adaptation a powerful probe into information processing. We used dynamic random dot kinematograms to test the magnitude and selectivity of adaptation effects in the middle temporal area (MT) and to compare them to effects on human motion discrimination. After 3 s of adaptation to a random dot pattern moving in the preferred direction, MT neuronal responses to subsequent test patterns were reduced by 26% on average compared with adaptation to a static pattern. This reduction in response magnitude was largely independent of what test stimulus was presented. However, adaptation in the opposite direction changed responses less often and very inconsistently. Therefore motion adaptation systematically and profoundly affects the neurons in MT representing the adapted direction, but much less those representing the opposite direction. In human psychophysical experiments, such adapting stimuli affected direction discrimination, biasing choices away from the adaptation direction. The magnitude of this perceptual shift was consistent with the magnitude of the changes seen in area MT, if one assumes that a motion comparison step occurs after MT.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-3077
pubmed:author
pubmed:issnType
Print
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3469-76
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Motion adaptation in area MT.
pubmed:affiliation
University of California, Davis Center for Neuroscience and Section of Neurobiology, Physiology, and Behavior, Davis, California 95616, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't