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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2002-12-5
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pubmed:abstractText |
Six patients with gastric cancer, stage IIIA to IV, received intraabdominal cisplatin (CDDP) at laporotomy. This was followed by postoperative intravenous infusion of mitomycin C (MMC), CDDP or fluorouracil (5-FU). When these patients recovered to the extent that permitted oral medication, an immunochemotherapeutic regimen containing either oral UFT (uracil and tegafur) or 5'-deoxy-5-fluorouridine (5'-DFUR), plus intravenous Lentinan (LNT) was administered for a period ranging from one and a half to two years. This postoperative immunochemotherapy was successful in all 6 patients. No relapse has been observed in any of them for at least 4 years. These findings indicate that the chemotherapeutic strategy of administering intraabdominal CDDP immediately after surgery, followed by postoperative immunochemotherapy with pyrimidine-fluoride products plus Lentinan on an outpatient basis may be useful in the treatment of T3 or T4 gastric carcinoma with metastasis in the regional lymph nodes.
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pubmed:language |
jpn
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0385-0684
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1989-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12465402-Adenocarcinoma,
pubmed-meshheading:12465402-Adjuvants, Immunologic,
pubmed-meshheading:12465402-Aged,
pubmed-meshheading:12465402-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12465402-Carcinoma, Signet Ring Cell,
pubmed-meshheading:12465402-Chemotherapy, Adjuvant,
pubmed-meshheading:12465402-Cisplatin,
pubmed-meshheading:12465402-Female,
pubmed-meshheading:12465402-Fluorouracil,
pubmed-meshheading:12465402-Humans,
pubmed-meshheading:12465402-Lentinan,
pubmed-meshheading:12465402-Lymph Nodes,
pubmed-meshheading:12465402-Lymphatic Metastasis,
pubmed-meshheading:12465402-Male,
pubmed-meshheading:12465402-Middle Aged,
pubmed-meshheading:12465402-Mitomycin,
pubmed-meshheading:12465402-Neoplasm Invasiveness,
pubmed-meshheading:12465402-Serous Membrane,
pubmed-meshheading:12465402-Stomach Neoplasms
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pubmed:year |
2002
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pubmed:articleTitle |
[Postoperative adjuvant immunochemotherapy using Lentinan for advanced gastric carcinoma patients with metastasis in the regional lymph nodes and serosal invasion].
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pubmed:affiliation |
Division of Surgery, Rakuwakai Otowa Hospital.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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