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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2002-12-4
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pubmed:abstractText |
N-acetyltransferase 2 (NAT2) is a key enzyme for the acetylation of sulfasalazine (SSZ). We examine whether there was a correlation between diplotype configurations (combinations of 2 haplotypes for a subject) at the NAT2 gene and the adverse effects of SSZ used for the treatment of rheumatoid arthritis (RA).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0315-162X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2492-9
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pubmed:dateRevised |
2010-9-8
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pubmed:meshHeading |
pubmed-meshheading:12465141-Acetylation,
pubmed-meshheading:12465141-Antirheumatic Agents,
pubmed-meshheading:12465141-Arthritis, Rheumatoid,
pubmed-meshheading:12465141-Arylamine N-Acetyltransferase,
pubmed-meshheading:12465141-Female,
pubmed-meshheading:12465141-Haplotypes,
pubmed-meshheading:12465141-Humans,
pubmed-meshheading:12465141-Male,
pubmed-meshheading:12465141-Polymerase Chain Reaction,
pubmed-meshheading:12465141-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:12465141-Sulfasalazine
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pubmed:year |
2002
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pubmed:articleTitle |
Adverse effects of sulfasalazine in patients with rheumatoid arthritis are associated with diplotype configuration at the N-acetyltransferase 2 gene.
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pubmed:affiliation |
Institute of Rheumatology and Division of Statistical Genetics, Tokyo Women's Medical University, Japan. tanaka@tkg.att.ne.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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