Source:http://linkedlifedata.com/resource/pubmed/id/12462151
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2002-12-3
|
pubmed:abstractText |
Pentacyclic triterpenes have been found in many plants and may be isolated from any part of the plant. Triterpene derivatives were shown to have biological activities including anti-HIV-1 and anti-cancer activities. The modes of action of the anti-HIV-1 triterpenes have been reported to be associated with the virus entry, reverse transcription, virus assembly and maturation. This review will focus on the mechanisms of action of anti-HIV triterpenes and the structural features that contribute to their anti-HIV-1 activity and site of action.
|
pubmed:language |
eng
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-HIV Agents,
http://linkedlifedata.com/resource/pubmed/chemical/HIV Protease Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Virus,
http://linkedlifedata.com/resource/pubmed/chemical/Reverse Transcriptase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Triterpenes
|
pubmed:status |
MEDLINE
|
pubmed:author | |
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
33-6
|
pubmed:dateRevised |
2005-11-16
|
pubmed:articleTitle |
Molecular targets of anti-HIV-1 triterpenes.
|
pubmed:affiliation |
Department of Microbiology, Meharry Medical College, 1005 DB Todd Blvd., Nashville, TN 37208, USA.
|