12459678

Source:http://linkedlifedata.com/resource/pubmed/id/12459678

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006400, umls-concept:C0014272, umls-concept:C0018787, umls-concept:C0034693, umls-concept:C0205191, umls-concept:C0242184, umls-concept:C0332157, umls-concept:C0521451, umls-concept:C1280500
pubmed:dateCreated	2002-12-2
pubmed:abstractText	Adaptation to chronic exposure to hypoxia alters energy metabolism in the heart, particularly in the left ventricle, which undergoes a loss in oxidative capacity. Highly lipophilic local anesthetics interfere with mitochondrial energy metabolism. The purpose of this study was to compare the effects of bupivacaine on mitochondrial energy metabolism in heart of rats subjected to normoxic or hypoxic environments.
pubmed:language	eng
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Local, http://linkedlifedata.com/resource/pubmed/chemical/Bupivacaine
pubmed:status	MEDLINE
pubmed:author	pubmed-author:ForestierFrançoisF, pubmed-author:MalgatMoniqueM, pubmed-author:MarthanRogerR, pubmed-author:MazatJean-PierreJP, pubmed-author:Nouette-GaulainKarineK, pubmed-author:SztarkFrançoisF
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1507-11
pubmed:dateRevised	2006-11-15
pubmed:articleTitle	Effects of bupivacaine on mitochondrial energy metabolism in heart of rats following exposure to chronic hypoxia.
pubmed:affiliation	Laboratoire d'Anesthésiologie (INSERM EMI 9929), Université Victor Segalen Bordeaux 2, F-33076 Bordeaux Cedex, France.