12459331

Source:http://linkedlifedata.com/resource/pubmed/id/12459331

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0033268, umls-concept:C0442335, umls-concept:C1564874
pubmed:dateCreated	2002-12-2
pubmed:abstractText	Recombinant adeno-associated viral (rAAV) vectors are being evaluated in animal models and humans. Pre-clinical data demonstrating vector safety, efficiency and efficacy have been used to initiate human clinical trials. The clinical manufacture of rAAV vectors has supported phase I and phase II trials, showing that adeno-associated virus serotype 2 vectors are safe when administered to humans.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/DK 58327, http://linkedlifedata.com/resource/pubmed/grant/EY 13729, http://linkedlifedata.com/resource/pubmed/grant/HL 51811, http://linkedlifedata.com/resource/pubmed/grant/HL 59412, http://linkedlifedata.com/resource/pubmed/grant/RR 16586
pubmed:language	eng
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/DNA, Recombinant
pubmed:status	MEDLINE
pubmed:author	pubmed-author:FlotteTerence RTR, pubmed-author:SnyderRichard ORO
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	418-23
pubmed:dateRevised	2007-11-15
pubmed:articleTitle	Production of clinical-grade recombinant adeno-associated virus vectors.
pubmed:affiliation	Powell Gene Therapy Center, University of Florida Genetics Institute, Department of Pediatrics, 1600 SW Archer Road, Gainesville, FL 32610-0266, USA.