Source:http://linkedlifedata.com/resource/pubmed/id/12458619
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| Predicate | Object |
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| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
2002-12-2
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| pubmed:abstractText |
The effects of dietary cis and trans a-linolenic acid (18:3n-3) on the FA composition of plasma, red blood cell, and liver phospholipids were studied in newborn piglets. Animals were fed for 14 d with one of three diets: a control diet (group A) containing cis 18:3n-3 at a level of 2.0% of total FA, a diet (group B) in which a part of the 18:3n-3 acid was isomerized (1.3% of cis 18:3n-3 and 0.7% of trans 18:3n-3), or a diet (group C) with 2.0% cis 18:3n-3 and 0.7% trans 18:3n-3. Feeding animals with diets containing trans 18:3n-3 resulted in the presence of trans isomers of 18:3n-3, trans isomers of EPA, and trans isomers of DHA in phospholipids; however, the level of total trans n-3 PUFA in tissues was less than 0.3% of total tissue FA. In group B, the reduction of dietary amounts of cis 18:3n-3 was associated with a decrease in individual and total cis n-3 PUFA. In contrast, in group C there was no decrease in tissue n-3 PUFA despite the increased dietary level of trans 18:3n-3. These results suggest that the isomerization of a part of dietary n-3 PUFA, leading to the reduction of their levels in the diet, could induce a decrease in n-3 PUFA in phospholipids. The physiological effects of trans PUFA are not known and should be considered in future studies.
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| pubmed:language |
eng
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| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:author | |
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
849-52
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| pubmed:dateRevised |
2006-11-15
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| pubmed:articleTitle |
FA composition of plasma, red blood cell, and liver phospholipids of newborn piglets fed trans isomers of alpha-linolenic acid.
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| pubmed:affiliation |
INRA, Unité de Nutrition Lipidique, 21065 Dijon Cedex, France.
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