12451608

Source:http://linkedlifedata.com/resource/pubmed/id/12451608

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0000768, umls-concept:C0003069, umls-concept:C0017262, umls-concept:C0023175, umls-concept:C0023816, umls-concept:C0027061, umls-concept:C0034493, umls-concept:C0185117, umls-concept:C0205217, umls-concept:C0521324, umls-concept:C2911684
pubmed:dateCreated	2002-11-26
pubmed:abstractText	Lipoprotein lipase (LPL) plays an important role in plasma lipoprotein metabolism and the uptake of free fatty acid in muscle. Previous studies using transgenic mice showed that increased LPL leads to myopathies, but these results were controversial. To examine this hypothesis, we studied LPL transgenic rabbits, and our results refute the suggested role of LPL in the pathogenesis of myopathies.
pubmed:language	eng
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Lipoprotein Lipase, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
pubmed:status	MEDLINE
pubmed:author	pubmed-author:FanJianglinJ, pubmed-author:IchikawaTomonagaT, pubmed-author:KitajimaShujiS, pubmed-author:KoikeTomonariT, pubmed-author:LiangJingyanJ, pubmed-author:UnokiHiroyukiH, pubmed-author:WangXiaofeiX, pubmed-author:WatanabeTeruoT
pubmed:copyrightInfo	Copyright 2002 Wiley Periodicals, Inc. Muscle Nerve 26: 823-827, 2002
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	823-7
pubmed:dateRevised	2006-11-15
pubmed:articleTitle	Increased expression of lipoprotein lipase in transgenic rabbits does not lead to abnormalities in skeletal and heart muscles.
pubmed:affiliation	Cardiovascular Disease Laboratory, Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba 305-8575, Japan.