Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-11-20
pubmed:abstractText
Antimicrobial susceptibility testing was performed on a total of 581 clinical Escherichia coli isolates from diarrhea and edema disease in pigs, from acute mastitis in dairy cattle, from urinary tract infections in dogs and cats, and from septicemia in laying hens collected in Switzerland between 1999 and 2001. Among the 16 antimicrobial agents tested, resistance was most frequent for sulfonamides, tetracycline, and streptomycin. Isolates from swine presented significantly more resistance than those from the other animal species. The distribution of the resistance determinants for sulfonamides, tetracycline, and streptomycin was assessed by hybridization and PCR in resistant isolates. Significant differences in the distribution of resistance determinants for tetracycline (tetA, tetB) and sulfonamides (sulII) were observed between the isolates from swine and those from the other species. Resistance to sulfonamides could not be explained by known resistance mechanisms in more than a quarter of the sulfonamide-resistant and sulfonamide-intermediate isolates from swine, dogs and cats. This finding suggests that one or several new resistance mechanisms for sulfonamides may be widespread among E. coli isolates from these animal species. The integrase gene (intI) from class I integrons was detected in a large proportion of resistant isolates in association with the sulI and aadA genes, thus demonstrating the importance of integrons in the epidemiology of resistance in clinical E. coli isolates from animals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0378-1135
pubmed:author
pubmed:issnType
Print
pubmed:day
2
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-84
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12441233-Animal Diseases, pubmed-meshheading:12441233-Animals, pubmed-meshheading:12441233-Cats, pubmed-meshheading:12441233-Cattle, pubmed-meshheading:12441233-Chickens, pubmed-meshheading:12441233-DNA, Bacterial, pubmed-meshheading:12441233-Dogs, pubmed-meshheading:12441233-Drug Resistance, Bacterial, pubmed-meshheading:12441233-Escherichia coli, pubmed-meshheading:12441233-Escherichia coli Infections, pubmed-meshheading:12441233-Female, pubmed-meshheading:12441233-Microbial Sensitivity Tests, pubmed-meshheading:12441233-Nucleic Acid Hybridization, pubmed-meshheading:12441233-Polymerase Chain Reaction, pubmed-meshheading:12441233-Streptomycin, pubmed-meshheading:12441233-Sulfonamides, pubmed-meshheading:12441233-Swine, pubmed-meshheading:12441233-Switzerland, pubmed-meshheading:12441233-Tetracycline
pubmed:year
2003
pubmed:articleTitle
Antimicrobial resistance and resistance gene determinants in clinical Escherichia coli from different animal species in Switzerland.
pubmed:affiliation
Institute for Veterinary Bacteriology, University of Bern, Länggass-Strasse 122, CH-3012 Bern, Switzerland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't