GENERIC 12441189

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0055522, umls-concept:C0220781, umls-concept:C1883254
pubmed:dateCreated	2002-11-20
pubmed:abstractText	We describe the synthesis of (25R)-cholest-5-en-3beta,26-diol ((25R)-26-hydroxycholesterol) from diosgenin in four steps in 58% overall, yield via a modified Clemmensen reduction followed by a Barton deoxygenation reaction.
pubmed:language	eng
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Hydroxycholesterols, http://linkedlifedata.com/resource/pubmed/chemical/cholest-5-ene-3 beta,26-diol
pubmed:status	MEDLINE
pubmed:author	pubmed-author:ChaiDepingD, pubmed-author:WilliamsJohn RJR, pubmed-author:WrightDominicD
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1041-4
pubmed:dateRevised	2006-11-15
pubmed:articleTitle	Synthesis of (25R)-26-hydroxycholesterol.
pubmed:affiliation	Department of Chemistry, Temple University, 13th & Norris Streets, Beury Hall (016-00), Philadelphia, PA 19122-2585, USA. john.r.williams@temple.edu