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rdf:type |
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lifeskim:mentions |
umls-concept:C0011860,
umls-concept:C0032405,
umls-concept:C0035647,
umls-concept:C0221099,
umls-concept:C0332281,
umls-concept:C0681850,
umls-concept:C1550501,
umls-concept:C1660757,
umls-concept:C1706203,
umls-concept:C1879547,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:dateCreated |
2002-11-19
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pubmed:abstractText |
We have previously shown that endothelial function is impaired not only in diabetes but also in subjects at risk of developing type 2 diabetes. We hypothesized that changes in the expression or activity of the endothelial isoform of nitric oxide synthase (eNOS), the receptor for advanced glycation end products (RAGE), and poly(ADP-ribose) polymerase (PARP) are related to this impairment.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3-nitrotyrosine,
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD31,
http://linkedlifedata.com/resource/pubmed/chemical/NOS3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Poly(ADP-ribose) Polymerases,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Tyrosine,
http://linkedlifedata.com/resource/pubmed/chemical/advanced glycosylation end-product...
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pubmed:status |
MEDLINE
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pubmed:author |
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2680-6
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pubmed:dateRevised |
2007-11-15
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pubmed:articleTitle |
Poly(ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity.
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pubmed:affiliation |
Institute of Human Physiology and Clinical Experimental Research, Semmelweis University, Budapest, Hungary.
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