Source:http://linkedlifedata.com/resource/pubmed/id/12433706
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2002-11-15
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pubmed:abstractText |
We conducted a prospective study on the association between supplemental vitamin E and colon cancer in 87,998 females from the Nurses' Health Study and 47, 344 males from the Health Professionals Follow-up Study. There was some suggestion that men with supplemental vitamin E intake of 300 IU/day or more may be at lower risk for colon cancer when compared with never users [multivariate relative risk (RR), 300-500 IU/day versus never users, 0.73 (95% confidence interval (CI), 0.52-1.03); >or=600 IU/day versus never users = 0.70 (95% CI = 0.38-1.29)], but CIs included 1. In women, there was no evidence for an inverse association between vitamin E supplementation and risk of colon cancer. Our findings do not provide consistent support for an inverse association between supplemental vitamin E and colon cancer risk. Considering the paucity of epidemiological data on this association, further studies of vitamin E and colon cancer are warranted.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antioxidants,
http://linkedlifedata.com/resource/pubmed/chemical/Ascorbic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Carotenoids,
http://linkedlifedata.com/resource/pubmed/chemical/Vitamin D,
http://linkedlifedata.com/resource/pubmed/chemical/Vitamin E
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pubmed:status |
MEDLINE
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pubmed:author | |
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1298-304
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pubmed:dateRevised |
2007-11-14
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pubmed:articleTitle |
A prospective study on supplemental vitamin e intake and risk of colon cancer in women and men.
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pubmed:affiliation |
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA. kana.wu@channing.harvard.edu
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