12433268

Source:http://linkedlifedata.com/resource/pubmed/id/12433268

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002395, umls-concept:C0017270, umls-concept:C0086418, umls-concept:C0086860, umls-concept:C0278372, umls-concept:C1364818, umls-concept:C1882417
pubmed:dateCreated	2002-11-15
pubmed:abstractText	Missense mutations in the amyloid precursor protein (APP) gene cause early-onset Alzheimer disease (AD). However, little is known regarding the effects of polymorphisms in regulatory sequences of APP on AD susceptibility.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AG07232, http://linkedlifedata.com/resource/pubmed/grant/AG08702
pubmed:language	eng
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Amyloid beta-Protein Precursor
pubmed:status	MEDLINE
pubmed:author	pubmed-author:ArriagaAlexA, pubmed-author:AthanEleni SES, pubmed-author:LeeJoseph HJH, pubmed-author:MayeuxRichard PRP, pubmed-author:TyckoBenjaminB
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1793-9
pubmed:dateRevised	2008-11-21
pubmed:articleTitle	Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease.
pubmed:affiliation	Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, NY, USA.