Linked Life Data

12428366

Source:http://linkedlifedata.com/resource/pubmed/id/12428366

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2002-11-13
pubmed:abstractText
An antisaccadic paradigm in which saccades are directed towards the mirror location opposite to that of target appearance has been thought to reflect frontal lobe function and a saccade-inhibitory mechanism. In order to clarify now the cortical mechanism differs between antisaccades (AS) and reflexive visually guided saccades (VS), we measured scalp EEG potentials preceding AS and VS in 9 young normal subjects, as well as the magnetic brain activities during AS and VS in 1 of them. Prior to the right and left saccades in both paradigms, our measurements revealed the appearance of a slowly developing negative potential, the presaccadic negativity (PSN), and then a steeper negative potential, the presaccadic steep negativity (PSSN). The onset of PSSN was significantly earlier and the maximum amplitude of PSSN was significantly greater in AS than in VS. The peak amplitude of PSSN at each middle electrode (Fz, Cz, Pz) was generally greater in AS than in VS in both directions of saccades. In one normal subject, the difference between AS and VS in the magnetic field distribution just prior to saccades in both directions was demonstrated as current dipoles on the bilateral frontal areas. Our results suggest that the activation of the bilateral frontal lobes is greater prior to AS than it is prior to VS.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0006-8969
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
803-10
pubmed:dateRevised
2007-2-22
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
[Cortical control of saccadic eye movements: a clinical electrophysiological study of antisaccades].
pubmed:affiliation
Department of Neurology, Tokyo Metropolitan Neurological Hospital, 2-6-1 Musashidai, Fuchu-shi, Tokyo 183-0042, Japan.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't