Linked Life Data

12428328

Source:http://linkedlifedata.com/resource/pubmed/id/12428328

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2002-11-13
pubmed:abstractText
A 64-year-old man was scheduled for transure thral resection of the prostate. The patient's medical history showed borderline diabetic state and two uncomplicated surgeries under spinal anesthesia. Spinal anesthesia was performed at the L 3/4 interspace using hyperbaric 0.24% dibucaine 2.2 ml, which was followed by general anesthesia because the anesthesia level had spread only to the lower left side of the body. On the next day, he complained of difficulty of defecation and urination combined with hypesthesia around the anus, which was diagnosed as cauda equina syndrome. The symptoms had not changed for three weeks. Then, there was a gradual recovery but slight hypesthesia remained even four months after the surgery. Speculation of this clinical etiology suggests that high concentration of dibucaine, having maldistributed inside the intrathecal space, affected cauda equina, which resulted in irreversible nerve damage. There were other risk factors for cauda equina syndrome in this patient such as lithotomy position, history of frequent spinal anesthesia, diabetes and advanced age. None of these are contraindication for spinal anesthesia. Many elderly patients particularly undergoing urological surgeries are likely to have such risk factors. Therefore at least dibucaine should be avoided for spinal anesthesia because of its high neurotoxicity compared with other local anesthetics.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-4892
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1151-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
[Dibucaine for spinal anesthesia is a probable risk for cauda equina syndrome].
pubmed:affiliation
Department of Anesthesiology, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, Tachikawa 190-8531.
pubmed:publicationType
Journal Article, English Abstract, Case Reports