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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-11-12
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pubmed:abstractText |
Vascular access dysfunction is the most important cause of morbidity and hospitalization in the hemodialysis population in the United States at a cost of well over one billion dollars per annum. Venous neointimal hyperplasia characterized by stenosis and subsequent thrombosis, is the major cause of polytetrafluoroethylene (PTFE) dialysis graft failure. Despite the magnitude of the problem, there are currently no effective therapies for the prevention or treatment of venous neointimal hyperplasia in PTFE dialysis grafts. We believe that this is partly due to the lack of a validated large animal model of arteriovenous stenosis that could be used to test out novel interventions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2272-80
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12427156-Animals,
pubmed-meshheading:12427156-Arteriovenous Shunt, Surgical,
pubmed-meshheading:12427156-Blood Vessel Prosthesis,
pubmed-meshheading:12427156-Cell Division,
pubmed-meshheading:12427156-Constriction, Pathologic,
pubmed-meshheading:12427156-Disease Models, Animal,
pubmed-meshheading:12427156-Dogs,
pubmed-meshheading:12427156-Endothelium, Vascular,
pubmed-meshheading:12427156-Graft Occlusion, Vascular,
pubmed-meshheading:12427156-Hyperplasia,
pubmed-meshheading:12427156-Macrophages,
pubmed-meshheading:12427156-Muscle, Smooth, Vascular,
pubmed-meshheading:12427156-Polytetrafluoroethylene,
pubmed-meshheading:12427156-Renal Dialysis,
pubmed-meshheading:12427156-Sheep,
pubmed-meshheading:12427156-Sus scrofa,
pubmed-meshheading:12427156-Tunica Intima
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pubmed:year |
2002
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pubmed:articleTitle |
Aggressive venous neointimal hyperplasia in a pig model of arteriovenous graft stenosis.
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pubmed:affiliation |
Department of Surgery, University of Cincinnati, Cincinnati, Ohio 45267, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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