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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-11-11
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|
pubmed:abstractText |
A comparison between a local anesthetic drug and the 5-hydroxytryptamine 3 (5-HT3) receptor antagonist tropisetron in treating tendopathies or periarthropathies revealed that tropisetron has a longer effect on resting pain and pain on movement than the local anesthetic drug. The most likely explanation for this effect probably is a blocking of stimulated 5-HT3 receptors at the nociceptors in conjunction with an inhibited release of substance P and other neurokines because of this blockage. Further studies will have to show whether the action of tropisetron in tendopathies is as favorable as that of corticosteroids.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0172-8172
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-21
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12426658-Anesthetics, Local,
pubmed-meshheading:12426658-Double-Blind Method,
pubmed-meshheading:12426658-Female,
pubmed-meshheading:12426658-Humans,
pubmed-meshheading:12426658-Indoles,
pubmed-meshheading:12426658-Infusions, Intralesional,
pubmed-meshheading:12426658-Injections, Intra-Articular,
pubmed-meshheading:12426658-Male,
pubmed-meshheading:12426658-Middle Aged,
pubmed-meshheading:12426658-Movement,
pubmed-meshheading:12426658-Pain,
pubmed-meshheading:12426658-Pain Measurement,
pubmed-meshheading:12426658-Prilocaine,
pubmed-meshheading:12426658-Serotonin Antagonists,
pubmed-meshheading:12426658-Tendinopathy,
pubmed-meshheading:12426658-Treatment Outcome
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pubmed:year |
2002
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|
pubmed:articleTitle |
Treatment of tendopathies with tropisetron.
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pubmed:affiliation |
Hochrhein-Institut für Rehabilitationsforschung, Bergseestrasse 61, 79713 Bad Säckingen, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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