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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2002-11-8
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|
pubmed:abstractText |
Rats reared in social isolation exhibit hyperactivity and specific attentional disturbances in later adult life. These behavioural abnormalities may be relevant to impulsivity and other neuropsychiatric syndromes such as attention-deficit hyperactivity disorder and schizophrenia where disturbances in circuitry involving the prefrontal cortex have been identified.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0033-3158
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
164
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
329-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12424557-Amphetamine,
pubmed-meshheading:12424557-Analysis of Variance,
pubmed-meshheading:12424557-Animals,
pubmed-meshheading:12424557-Attention,
pubmed-meshheading:12424557-Behavior, Animal,
pubmed-meshheading:12424557-Brain Chemistry,
pubmed-meshheading:12424557-Central Nervous System Stimulants,
pubmed-meshheading:12424557-Choice Behavior,
pubmed-meshheading:12424557-Dopamine,
pubmed-meshheading:12424557-Dose-Response Relationship, Drug,
pubmed-meshheading:12424557-Impulsive Behavior,
pubmed-meshheading:12424557-Male,
pubmed-meshheading:12424557-Microdialysis,
pubmed-meshheading:12424557-Motor Activity,
pubmed-meshheading:12424557-Neural Inhibition,
pubmed-meshheading:12424557-Photic Stimulation,
pubmed-meshheading:12424557-Prefrontal Cortex,
pubmed-meshheading:12424557-Psychomotor Performance,
pubmed-meshheading:12424557-Rats,
pubmed-meshheading:12424557-Reaction Time,
pubmed-meshheading:12424557-Serotonin,
pubmed-meshheading:12424557-Social Isolation,
pubmed-meshheading:12424557-Visual Perception
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pubmed:year |
2002
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|
pubmed:articleTitle |
Specific abnormalities in serotonin release in the prefrontal cortex of isolation-reared rats measured during behavioural performance of a task assessing visuospatial attention and impulsivity.
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pubmed:affiliation |
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK. jwd20@cus.cam.ac.uk
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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