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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2002-11-8
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pubmed:abstractText |
The multidrug resistance (mdr) gene family encodes the drug transport macromolecule P-glycoprotein (P-gp), which contributes to the functionality of the blood-brain barrier. Recent evidence suggests that P-gp-mediated drug extrusion may play a facilitatory role in refractory epilepsy. We investigated the regional expression of mdr genes in genetically epilepsy-prone rat (GEPR) brain after a single audiogenic seizure.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0013-9580
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1318-23
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:12423380-ATP-Binding Cassette Transporters,
pubmed-meshheading:12423380-Animals,
pubmed-meshheading:12423380-Brain,
pubmed-meshheading:12423380-Cerebral Cortex,
pubmed-meshheading:12423380-Epilepsy,
pubmed-meshheading:12423380-Genes, MDR,
pubmed-meshheading:12423380-Genetic Predisposition to Disease,
pubmed-meshheading:12423380-Male,
pubmed-meshheading:12423380-Mesencephalon,
pubmed-meshheading:12423380-P-Glycoproteins,
pubmed-meshheading:12423380-Rats,
pubmed-meshheading:12423380-Rats, Mutant Strains,
pubmed-meshheading:12423380-Seizures
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pubmed:year |
2002
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pubmed:articleTitle |
Regional expression of multidrug resistance genes in genetically epilepsy-prone rat brain after a single audiogenic seizure.
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pubmed:affiliation |
Epilepsy Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow, Scotland.
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pubmed:publicationType |
Journal Article
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