Source:http://linkedlifedata.com/resource/pubmed/id/12423091
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0002068,
umls-concept:C0205431,
umls-concept:C0205460,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0542559,
umls-concept:C1136012,
umls-concept:C1260969,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C1875307,
umls-concept:C1881759,
umls-concept:C2607943,
umls-concept:C2926606
|
| pubmed:issue |
23
|
| pubmed:dateCreated |
2002-11-8
|
| pubmed:abstractText |
The disclosure herein describes the synthesis of 10,11-dehydro-13,14-desoxy-27-trifluoro-[17]epothilone B via a stereoselective ring-closing metathesis and provides early biological evaluation data pertinent to this compound. [reaction: see text]
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
1523-7060
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
14
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
4081-4
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading | |
| pubmed:year |
2002
|
| pubmed:articleTitle |
On the introduction of a trifluoromethyl substituent in the epothilone setting: chemical issues related to ring forming olefin metathesis and earliest biological findings.
|
| pubmed:affiliation |
Laboratories for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10021, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|