Linked Life Data

12421319

Source:http://linkedlifedata.com/resource/pubmed/id/12421319

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2002-11-7
pubmed:abstractText
We report here transcriptional analyses of a cyanobacterial gene encoding an aminoacyl-tRNA synthetase (aaRS), the gltX gene from Synechoccocus sp. PCC 7942, coding for the glutamyl-tRNA synthetase. We show that the transcript levels of gltX in Synechococcus depend on nitrogen availability and do not increase with the growth rate, which is at odds with observations from other bacteria. We also demonstrate the involvement of the cyanobacterial global regulator NtcA in transcriptional control of gltX according to nitrogen status. Our results support a regulatory model in which the gltX transcript level is finely tuned by a dynamic equilibrium between activation and repression relying upon the cellular concentration of NtcA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0950-382X
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1157-67
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Expression of the glutamyl-tRNA synthetase gene from the cyanobacterium Synechococcus sp PCC 7942 depends on nitrogen availability and the global regulator NtcA.
pubmed:affiliation
Unité Mixte de Recherche, Centre National de la Recherche Scientifique, Paris, Cedex, France. ignacio.luque@ua.es
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't