Linked Life Data

12417221

Source:http://linkedlifedata.com/resource/pubmed/id/12417221

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2002-11-5
pubmed:abstractText
Different physiological approaches demonstrated motor system hyperexcitability in amyotrophic lateral sclerosis (ALS), probably reflecting excitotoxic mechanisms. Transcranial magnetic stimulation (TMS) showed that both increased excitability of corticomotoneurons and reduced intracortical inhibition (ICI) contribute to motor cortex hyperexcitability, but the importance of these factors in inducing this cortical dysfunction is unknown. The aim of the study was to establish how different mechanisms interact to promote motor system hyperexcitability in ALS in relation to clinical features.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1388-2457
pubmed:author
pubmed:issnType
Print
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1688-97
pubmed:dateRevised
2008-9-10
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Different mechanisms contribute to motor cortex hyperexcitability in amyotrophic lateral sclerosis.
pubmed:affiliation
Department of Neurological Sciences and Vision, Section of Clinical Neurology, University of Verona, Ospedale Policlinico G.B. Rossi, piazzale Scuro, 37134 Verona, Italy. gi.zanette@libero.it
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't