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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2002-11-5
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pubmed:abstractText |
In human serum, type-5 tartrate-resistant acid phosphatase (TRACP) exists as two closely related isoforms: 5a and 5b. Serum isoform 5b is an osteoclast product that reflects bone resorption rate and is frequently increased in diseases of increased bone turnover. Isoform 5a protein is often increased in rheumatoid arthritis (RA) sera and may be a product of inflammatory macrophages. Our objective was to compare the biochemical characteristics of TRACP 5a and 5b.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
326
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12417102-4-Nitrophenylphosphatase,
pubmed-meshheading:12417102-Acid Phosphatase,
pubmed-meshheading:12417102-Animals,
pubmed-meshheading:12417102-Blotting, Western,
pubmed-meshheading:12417102-CHO Cells,
pubmed-meshheading:12417102-Cloning, Molecular,
pubmed-meshheading:12417102-Cricetinae,
pubmed-meshheading:12417102-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:12417102-Genetic Vectors,
pubmed-meshheading:12417102-Histocytochemistry,
pubmed-meshheading:12417102-Humans,
pubmed-meshheading:12417102-Hydrogen-Ion Concentration,
pubmed-meshheading:12417102-Isoenzymes,
pubmed-meshheading:12417102-Recombinant Proteins,
pubmed-meshheading:12417102-Time Factors,
pubmed-meshheading:12417102-Transfection
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pubmed:year |
2002
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pubmed:articleTitle |
Stable expression of human tartrate-resistant acid phosphatase isoforms by CHO cells.
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pubmed:affiliation |
Special Hematology Laboratory, Veterans Administration Medical Center, 800 Zorn Avenue (151), Louisville, KY 40206, USA. anthony.janckila@med.va.gov
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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