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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2002-11-5
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pubmed:abstractText |
Increasing evidence supports the role of genetic factors in susceptibility to infectious diseases, including chronic periodontitis. The role of genetic factors in phenotypic expression can be estimated from the degree of resemblance between relatives, as compared with that of unrelated members of a population. Heritability is an estimate of the proportion of total phenotypic variation of a quantitative trait, which is attributable to genetic factors, and is based on the variance within versus between family members. The aim of this study was to determine whether there is a familial basis for periodontal disease status in an untreated population in Guatemala using heritability estimates as a measure of familial clustering of disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-3492
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1160-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12416774-Adult,
pubmed-meshheading:12416774-Analysis of Variance,
pubmed-meshheading:12416774-Bacterial Infections,
pubmed-meshheading:12416774-Dental Plaque Index,
pubmed-meshheading:12416774-Disease Transmission, Infectious,
pubmed-meshheading:12416774-Family Health,
pubmed-meshheading:12416774-Female,
pubmed-meshheading:12416774-Guatemala,
pubmed-meshheading:12416774-Humans,
pubmed-meshheading:12416774-Male,
pubmed-meshheading:12416774-Middle Aged,
pubmed-meshheading:12416774-Periodontal Attachment Loss,
pubmed-meshheading:12416774-Periodontal Index,
pubmed-meshheading:12416774-Periodontitis,
pubmed-meshheading:12416774-Quantitative Trait, Heritable,
pubmed-meshheading:12416774-Siblings,
pubmed-meshheading:12416774-Smoking,
pubmed-meshheading:12416774-Space-Time Clustering,
pubmed-meshheading:12416774-Spouses,
pubmed-meshheading:12416774-Statistics, Nonparametric
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pubmed:year |
2002
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pubmed:articleTitle |
The effect of shared genetic and environmental factors on periodontal disease parameters in untreated adult siblings in Guatemala.
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pubmed:affiliation |
Department of Periodontics, Indiana University School of Dentistry, Indianapolis 46202, USA. sdowsett@iupui.edu
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pubmed:publicationType |
Journal Article
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