Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1975-7-23
pubmed:abstractText
Use of synthetic materials in herniplasty has been a controversial issue. In order to determine the influence of Mersilene mesh on the strength of healing abdominal wounds and its effectiveness in repair of hernia, experimental and clinical studies were undertaken. Experimental study included 175 male rats divided into three groups subjected to either: 1) an incision made only through the skin and closed with 3-0 silk sutures; 2) a 2.5 cm midline incision through the musculature and peritoneum closed with 2-0 Mersilene suture; or 3) the same procedure as group 2 with the addition of a Mersilene mesh onlay graft. Bursting strength of abdominal wounds as determined in all groups at intervals. Wounds of the group treated with the mesh exhibited significantly greater (P less than 0.01) bursting strength. Clinical trial consisted of 100 consecutive adult patients in which an onlay graft of Mersilene mesh was used in the hernioplasty. Mesh was used as an adjunct in patients with: 1) large ventral hernias; 2) direct hernias resulting from severely attenuated transversialis fascia; 3) indirect hernias associated with a large internal ring and a weak posterior inguinal wall; or 4) combined direct and indirect hernias. All were followed for a minimum of one year to determine the incidence of complication and rate of recurrence. This study suggests that: 1) Mersilene mesh increases the strength of healing abdominal wounds in rats; and 2) repair of large hernias with Mersilene mesh results in an acceptable morbidity and a lowered rate of recurrence.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-13455371, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14011096, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14048019, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14065717, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14260029, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14446350, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14470215, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14809566, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-14884103, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-4642709, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-4910229, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-5332453, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-5451191, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-5635188, http://linkedlifedata.com/resource/pubmed/commentcorrection/124162-6016270
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0003-4932
pubmed:author
pubmed:issnType
Print
pubmed:volume
181
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
728-34
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
The use of Mersilene mesh in repair of abdominal wall hernias: a clinical and experimental study.
pubmed:publicationType
Journal Article