Source:http://linkedlifedata.com/resource/pubmed/id/12415595
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2002-11-4
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pubmed:abstractText |
To determine whether mutations in the bone morphogenetic protein receptor 2 gene (BMPR2), initially reported in primary pulmonary hypertension, were present in patients with pulmonary arterial hypertension and scleroderma spectrum of disease. Methods. BMPR2 gene mutations were determined using nucleic acid sequencing in 24 patients with pulmonary arterial hypertension and scleroderma spectrum of disease and in 2 control groups, 96 healthy North American individuals and 100 Israeli Ashkenazi Jews. The patients also had antinuclear antibody determinations and underwent right heart catheterization.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0315-162X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2379-81
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12415595-Adult,
pubmed-meshheading:12415595-Aged,
pubmed-meshheading:12415595-Bone Morphogenetic Protein Receptors, Type II,
pubmed-meshheading:12415595-DNA Mutational Analysis,
pubmed-meshheading:12415595-Female,
pubmed-meshheading:12415595-Genetic Testing,
pubmed-meshheading:12415595-Humans,
pubmed-meshheading:12415595-Hypertension, Pulmonary,
pubmed-meshheading:12415595-Jews,
pubmed-meshheading:12415595-Male,
pubmed-meshheading:12415595-Middle Aged,
pubmed-meshheading:12415595-Mutation,
pubmed-meshheading:12415595-Polymorphism, Genetic,
pubmed-meshheading:12415595-Protein-Serine-Threonine Kinases,
pubmed-meshheading:12415595-Scleroderma, Systemic
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pubmed:year |
2002
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pubmed:articleTitle |
Pulmonary hypertension in scleroderma spectrum of disease: lack of bone morphogenetic protein receptor 2 mutations.
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pubmed:affiliation |
Department of Medicine, Columbia University, New York, New York 10032, USA. jhm4@columbia.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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