|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2002-11-4
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|
pubmed:abstractText |
We demonstrate by an ELISA the presence of antibodies in human filarial sera that react with diethylcarbamazine (DEC); they appear to be primarily filarial antibodies cross-reacting with DEC skeleton, since affinity-purified DEC antibodies strongly react with Wuchereria bancrofti microfilariae. These observations indicate a possible antigenic mimicry between the drug and some parasite component.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0009-9104
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
78
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
219-23
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|
pubmed:dateRevised |
2009-11-18
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|
pubmed:meshHeading |
pubmed-meshheading:12412752-Animals,
pubmed-meshheading:12412752-Antibodies, Helminth,
pubmed-meshheading:12412752-Antibody Specificity,
pubmed-meshheading:12412752-Antigens, Helminth,
pubmed-meshheading:12412752-Case-Control Studies,
pubmed-meshheading:12412752-Cross Reactions,
pubmed-meshheading:12412752-Diethylcarbamazine,
pubmed-meshheading:12412752-Filariasis,
pubmed-meshheading:12412752-Humans,
pubmed-meshheading:12412752-Microfilaria,
pubmed-meshheading:12412752-Molecular Mimicry,
pubmed-meshheading:12412752-Wuchereria bancrofti
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|
pubmed:year |
1989
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|
pubmed:articleTitle |
Antibodies in human filariasis sera react with diethylcarbamazine.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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