Source:http://linkedlifedata.com/resource/pubmed/id/12412738
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-11-4
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pubmed:abstractText |
We present the case of a 71 year-old man with secondary acute myeloblastic leukemia, who was successfully treated with low dose melphalan plus Epo plus G-CSF. We treated the patient with 2 mg of melphalan once a day orally, G-CSF 5 mg/kg 3 times a week and Epo 10.000 ui subcutaneously 3 times a week until the maximum response was obtained. Complete remission was achieved after 16 weeks of continuous treatment. Treatment-related toxicity was not significant. We recommend the use of low dose melphalan in elderly patients with high risk MDS as a treatment option.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0017-6559
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
169-73
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12412738-Aged,
pubmed-meshheading:12412738-Anemia, Refractory, with Excess of Blasts,
pubmed-meshheading:12412738-Drug Therapy, Combination,
pubmed-meshheading:12412738-Erythropoietin,
pubmed-meshheading:12412738-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:12412738-Humans,
pubmed-meshheading:12412738-Leukemia, Myeloid, Acute,
pubmed-meshheading:12412738-Male,
pubmed-meshheading:12412738-Melphalan,
pubmed-meshheading:12412738-Myelodysplastic Syndromes,
pubmed-meshheading:12412738-Remission Induction,
pubmed-meshheading:12412738-Risk Assessment
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pubmed:year |
2002
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pubmed:articleTitle |
Low dose melphalan is a treatment option in elderly patients with high risk myelodysplastic syndrome or secondary acute myeloblastic leukaemia.
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pubmed:affiliation |
First Department of Internal Medicine, University of Athens School of Medicine, Laiko General Hospital, Greece.
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pubmed:publicationType |
Journal Article,
Case Reports
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