Clinical outcome in leukemia patients transplanted from one-haplotype mismatched donors has been largely disappointing because of the high incidence of severe graft-vs-host disease in T-replete transplants or high rejection rates in T-cell-depleted transplants.
Hematopoietic Stem Cell Transplantation Program, Section of Hematology, Department of Internal and Experimental Medicine, University of Perugia, Italy. aversa@unipg.it