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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5-6
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pubmed:dateCreated |
2002-10-31
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pubmed:abstractText |
5-Fluorouracil (5-FU) is a widely used for colorectal carcinoma. However, the therapeutic effect of 5-FU differs among patients. This difference may be based on the difference in sensitivity of carcinoma cells to 5-FU. The activities of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) are reported to be correlated with cancer cell sensitivity against 5-FU in vitro. We evaluated whether TP and DPD are useful markers of tumor sensitivity for 5-FU in colorectal carcinomas.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1435-2443
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
387
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
240-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12410361-Aged,
pubmed-meshheading:12410361-Aged, 80 and over,
pubmed-meshheading:12410361-Antimetabolites, Antineoplastic,
pubmed-meshheading:12410361-Chemotherapy, Adjuvant,
pubmed-meshheading:12410361-Colorectal Neoplasms,
pubmed-meshheading:12410361-Dihydrouracil Dehydrogenase (NADP),
pubmed-meshheading:12410361-Drug Screening Assays, Antitumor,
pubmed-meshheading:12410361-Fluorouracil,
pubmed-meshheading:12410361-Humans,
pubmed-meshheading:12410361-Oxidoreductases,
pubmed-meshheading:12410361-Prognosis,
pubmed-meshheading:12410361-Survival Analysis,
pubmed-meshheading:12410361-Thymidine Phosphorylase
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pubmed:year |
2002
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pubmed:articleTitle |
Thymidine phosphorylase and dihydropyrimidine dehydrogenase activity in colorectal carcinoma and patients prognosis.
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pubmed:affiliation |
Division of Operating Room, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. masaike@grape.med.tottori-u.ac.jp
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pubmed:publicationType |
Journal Article
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