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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2002-10-31
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pubmed:abstractText |
The availability of a draft human genome sequence and ability to monitor the transcription of thousands of genes with DNA microarrays has necessitated the need for new computational tools that can analyze cis-regulatory elements controlling genes that display similar expression patterns. We have developed a tool designated EZ-Retrieve that can: (i) retrieve any particular region of human genome sequence from the NCBI database and (ii) analyze retrieved sequences for putative transcription factor-binding sites (TFBSs) as they appear on the TRANSFAC database. The tool is web-based, user-friendly and offers both batch sequence retrieval and batch TFBS prediction. A major application of EZ-Retrieve is the analysis of co-expressed genes that are highlighted as expression clusters in DNA microarray experiments.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-10404615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-10447504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-10656985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11125071,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11125113,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11156620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11159908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11175784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11237011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11547334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11574681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11581155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11586286,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11751235,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-11805330,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-12176925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12409480-9922398
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1362-4962
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e121
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:12409480-Animals,
pubmed-meshheading:12409480-Base Sequence,
pubmed-meshheading:12409480-Binding Sites,
pubmed-meshheading:12409480-Cell Cycle Proteins,
pubmed-meshheading:12409480-Computational Biology,
pubmed-meshheading:12409480-DNA,
pubmed-meshheading:12409480-DNA-Binding Proteins,
pubmed-meshheading:12409480-Databases, Genetic,
pubmed-meshheading:12409480-Drosophila melanogaster,
pubmed-meshheading:12409480-E2F Transcription Factors,
pubmed-meshheading:12409480-Gene Expression Regulation,
pubmed-meshheading:12409480-Genes, Insect,
pubmed-meshheading:12409480-Genome, Human,
pubmed-meshheading:12409480-Humans,
pubmed-meshheading:12409480-Information Storage and Retrieval,
pubmed-meshheading:12409480-Internet,
pubmed-meshheading:12409480-Molecular Sequence Data,
pubmed-meshheading:12409480-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:12409480-Response Elements,
pubmed-meshheading:12409480-Software,
pubmed-meshheading:12409480-Transcription Factors
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pubmed:year |
2002
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pubmed:articleTitle |
EZ-Retrieve: a web-server for batch retrieval of coordinate-specified human DNA sequences and underscoring putative transcription factor-binding sites.
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pubmed:affiliation |
Center for Applied Genomics, Public Health Research Institute, 225 Warren Street, ICPH W420M, Newark, NJ 07103, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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