Linked Life Data

12407914

Source:http://linkedlifedata.com/resource/pubmed/id/12407914

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2002-10-31
pubmed:abstractText
The target of our study was the determination of urinary t,t muconic acid concentration, as a biomarker of benzene intake in a population. Urinary samples of 101 subjects, males and females were obtained to whom. Information regarding modification and confounding factors were recorded by questionnaire. The samples were analysed by HPLC, after extraction of trans,trans muconic acid on strong anionic exchange cartridges. In these analytical conditions the detection limit with good care is 10 micrograms/l. A concentration range from 10 to 1300 micrograms/l was found. High levels found in the population could explained by confounding factors present. The obtained results were correlated with sex, age and smoking or non smoking. There was a significant difference in mean concentrations between heavy smokers (160 micrograms/l) and non smokers (110 micrograms/l), that showed tobacco as an interference factor. The study showed that it is strictly necessary carry out a thorough anamnesis before sampling with the objective of finding eventual interference factors such as smoking, diet and drugs taken.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-4592
pubmed:author
pubmed:issnType
Print
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
911-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Determination of urinary t-t muconic acid as biomarker of environmental benzene intake and its interference factors.
pubmed:affiliation
Sez. Medicina del Lavoro, Università degli Studi di Genova Largo R. Benzi 10, 16132 Genova. valter@unige.it
pubmed:publicationType
Journal Article