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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2002-10-30
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pubmed:abstractText |
Narcolepsy is strongly associated with the presence of HLA DQB1*0602. This and other evidence suggests that human narcolepsy is an autoimmune disease. This is in distinction to that found in canine models where hypocretin receptor 2 mutations are etiologic. We decided to test for the presence of several neuron-specific and organ-specific autoantibodies to see if they were present in HLA DQB1*0602-associated or cataplexy-associated narcolepsy or could serve as a serologic marker of the illness.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamate Decarboxylase,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQ Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQ beta-Chains,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQB1 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Neuropeptide,
http://linkedlifedata.com/resource/pubmed/chemical/Thyroglobulin,
http://linkedlifedata.com/resource/pubmed/chemical/amphiphysin,
http://linkedlifedata.com/resource/pubmed/chemical/glutamate decarboxylase 2,
http://linkedlifedata.com/resource/pubmed/chemical/orexin receptors
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0161-8105
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
719-23
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12405606-Adult,
pubmed-meshheading:12405606-Antibodies,
pubmed-meshheading:12405606-Glutamate Decarboxylase,
pubmed-meshheading:12405606-HLA-DQ Antigens,
pubmed-meshheading:12405606-HLA-DQ beta-Chains,
pubmed-meshheading:12405606-Humans,
pubmed-meshheading:12405606-Isoenzymes,
pubmed-meshheading:12405606-Membrane Glycoproteins,
pubmed-meshheading:12405606-Narcolepsy,
pubmed-meshheading:12405606-Nerve Tissue Proteins,
pubmed-meshheading:12405606-Neurons,
pubmed-meshheading:12405606-Point Mutation,
pubmed-meshheading:12405606-Receptors, G-Protein-Coupled,
pubmed-meshheading:12405606-Receptors, Neuropeptide,
pubmed-meshheading:12405606-Thyroglobulin
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pubmed:year |
2002
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pubmed:articleTitle |
Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602.
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pubmed:affiliation |
Department of Psychiatry, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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