Linked Life Data

12403940

Source:http://linkedlifedata.com/resource/pubmed/id/12403940

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2002-10-29
pubmed:abstractText
The standard reconstruction after esophagectomy is the formation of a gastric tube with partial devascularization of the lesser curvature. The purpose of this experimental study was to establish an animal model in order to analyze microcirculation associated with the formation of a gastric tube. In 17 pigs tissue perfusion was measured with a laser Doppler imager (LDI) and partial tissue oxygen pressure (ptO(2)) with a Clark-type polarographic oxygen electrode before and after formation of a gastric tube in well-defined regions of the stomach. The operative procedure included the dissection of the left gastric and short gastric arteries; the left gastroepiploic artery along the greater curvature was preserved. LDI and ptO(2) baseline measurement were significantly lower in the fundus compared to the antrum and corpus. After formation of a gastric tube LDI and ptO(2) baseline values calculated from the mean measurements of the antrum, corpus and fundus decreased significantly (LDI: 1,099 PU +/- 228 SD to 601 PU +/- 125 SD, p < 0.0001; ptO(2): 50.8 mm Hg +/- 5.9 SD to 40.7 mm Hg +/- 9.3 SD, p = 0.0003). Microcirculatory changes did not correlate with changes of cardiac output and systemic vascular resistance. This study suggests that the pig is an appropriate model to investigate microcirculation associated with gastric tube formation. Its use for esophageal reconstruction by pull-up of the gastric interponate is limited.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-312X
pubmed:author
pubmed:copyrightInfo
Copyright 2002 S. Karger AG, Basel
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
411-7
pubmed:dateRevised
2006-11-30
pubmed:meshHeading
pubmed:articleTitle
Microcirculatory changes associated with gastric tube formation in the pig.
pubmed:affiliation
Department of Visceral and Vascular Surgery, Informatics and Epidemiology, University of Cologne, Germany. Wolfgang.Schröder@Uni-Koeln.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't