Linked Life Data

12402804

Source:http://linkedlifedata.com/resource/pubmed/id/12402804

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2002-10-18
pubmed:abstractText
The diffuse infiltrative lymphocytosis syndrome (DILS) in HIV-infected persons is characterized by a persistent circulating CD8+ lymphocytosis. Certain HIV-infected persons appear to respond to their infection by developing an oligoclonal expansion of CD8+ lymphocytes. These cells infiltrate multiple organs, but the salivary glands and the lung constitute the major sites involved in this process. This infiltrative process resembles in many aspects a Sjögren-like syndrome, owing to the visceral lymphocytic infiltration. Unilateral parotid gland enlargement in a patient with HIV infection should prompt clinicians to suspect DILS. In addition, clinicians should be aware that the pulmonary process associated with DILS may mimic clinically and radiographically the pneumonic process caused by Pneumocystis carinii. Other manifestations of DILS to consider include a severe form of peripheral neuropathy; lymphocytic infiltration of the liver, evident as hepatitis; myositis; and lymphocytic interstitial nephritis.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
X
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1053-0894
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
408-13
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Diagnosis of diffuse CD8+ lymphocytosis syndrome in HIV-infected patients.
pubmed:affiliation
Emory University School of Medicine, Atlanta, Georgia, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.