12398958

Source:http://linkedlifedata.com/resource/pubmed/id/12398958

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0021107, umls-concept:C0038257, umls-concept:C0221464, umls-concept:C1253959, umls-concept:C1522318
pubmed:issue	9
pubmed:dateCreated	2002-10-25
pubmed:abstractText	The sirolimus-eluting stent (SES) is emerging as a potential solution for the prevention of restenosis. Although the outcome of side branches after stenting with an uncoated metal stent (UMS) has been reported, the fate of side branches after SES implantation is unknown. Furthermore, the absence of spontaneous recanalization of occluded side branches following intracoronary brachytherapy has been previously described and has been related to a delayed healing process. We assessed the procedural and 6-month follow-up angiograms of 238 patients enrolled in the RAVEL study, a double-blind controlled trial of the SES versus the UMS. Any side branch seen on the preprocedure angiogram and subsequently covered by the stent was evaluated. The side branch Thrombolysis In Myocardial Infarction (TIMI) flow grade was assessed at baseline and at follow-up by 2 observers. One hundred twenty-eight patients with > or =1 side branches were identified (63 patients in the SES group with 118 side branches, 65 patients in the UMS group with 124 side branches). Side branch occlusion occurred after stenting in 12 branches (10%) in the SES group and in 9 branches (7%) in the UMS group (p = NS). Of these occluded branches, spontaneous recanalization was observed in 11 branches (92%) in the SES group and in 6 branches (67%) in the UMS group at follow-up angiography (p = NS). Thus, the fate of side branches after SES implantation is favorable and at least as good as after UMS implantation.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0207277
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Coated Materials, Biocompatible, http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents, http://linkedlifedata.com/resource/pubmed/chemical/Sirolimus
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	0002-9149
pubmed:author	pubmed-author:DegertekinMuzafferM, pubmed-author:MoriceMarie ClaudeMC, pubmed-author:RegarEvelynE, pubmed-author:SerruysPatrick WPW, pubmed-author:SousaJ EduardoJE, pubmed-author:TanabeKengoK, pubmed-author:WülfertEgonE, pubmed-author:van DomburgRon TRT
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	90
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	937-41
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:12398958-Blood Vessel Prosthesis Implantation, pubmed-meshheading:12398958-Coated Materials, Biocompatible, pubmed-meshheading:12398958-Combined Modality Therapy, pubmed-meshheading:12398958-Coronary Angiography, pubmed-meshheading:12398958-Coronary Artery Disease, pubmed-meshheading:12398958-Coronary Restenosis, pubmed-meshheading:12398958-Coronary Vessels, pubmed-meshheading:12398958-Double-Blind Method, pubmed-meshheading:12398958-Follow-Up Studies, pubmed-meshheading:12398958-Humans, pubmed-meshheading:12398958-Immunosuppressive Agents, pubmed-meshheading:12398958-Predictive Value of Tests, pubmed-meshheading:12398958-Sirolimus, pubmed-meshheading:12398958-Stents, pubmed-meshheading:12398958-Treatment Outcome, pubmed-meshheading:12398958-Ultrasonography, Interventional
pubmed:year	2002
pubmed:articleTitle	Fate of side branches after coronary arterial sirolimus-eluting stent implantation.
pubmed:affiliation	Thoraxcenter, Rotterdam, The Netherlands.
pubmed:publicationType	Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Evaluation Studies