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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2002-10-24
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pubmed:abstractText |
Heart transplantation is an established tool for the treatment of terminal heart failure. Hyperlipidemia is a common problem following heart transplantation and has been implicated as an additional risk factor in the development of transplant coronary artery disease (TxCAD). Therefore, heart recipients are commonly treated with inhibitors of cholesterol synthesis (HMG-CoA reductase inhibitors). However, these patients have an increased risk of developing rhabdomyolysis due to elevated concentrations of HMG-CoA reductase inhibitors under co-administration with the immunosuppressive cyclosporin A (CsA).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0946-1965
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
439-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12395976-Anticholesteremic Agents,
pubmed-meshheading:12395976-Cholesterol,
pubmed-meshheading:12395976-Creatinine,
pubmed-meshheading:12395976-Cyclosporine,
pubmed-meshheading:12395976-Drug Interactions,
pubmed-meshheading:12395976-Drug Monitoring,
pubmed-meshheading:12395976-Female,
pubmed-meshheading:12395976-Heart Transplantation,
pubmed-meshheading:12395976-Humans,
pubmed-meshheading:12395976-Hypercholesterolemia,
pubmed-meshheading:12395976-Immunosuppressive Agents,
pubmed-meshheading:12395976-L-Lactate Dehydrogenase,
pubmed-meshheading:12395976-Male,
pubmed-meshheading:12395976-Middle Aged,
pubmed-meshheading:12395976-Pravastatin,
pubmed-meshheading:12395976-Time Factors,
pubmed-meshheading:12395976-Transferases,
pubmed-meshheading:12395976-Triglycerides
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pubmed:year |
2002
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pubmed:articleTitle |
Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A.
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pubmed:affiliation |
Medizinische Klinik I, Krankenhaus Hoyerswerda.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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