Linked Life Data

12392860

Source:http://linkedlifedata.com/resource/pubmed/id/12392860

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2002-10-23
pubmed:abstractText
The aim of this study was to investigate the possible association between the inducible nitric oxide synthase (NOS2) gene promoter polymorphism, CCTTTn microsatellite, with celiac disease susceptibility. We carried out a familial study in which 53 Spanish families were genotyped by a polymerase chain reaction (PCR)-based method combined with fluorescent technology. A transmission disequilibrium test was performed to investigate the transmission pattern of the different CCTTTn alleles from parents to affected offspring. The test did not reach any statistically significant difference because none of the CCTTTn repeats was shown to be significantly transmitted to the affected siblings. Our data suggest that the CCTTTn pentanucleotide microsatellite in the NOS2 gene promoter does not play a major role in celiac disease development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0198-8859
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1062-5
pubmed:dateRevised
2011-10-27
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Polymorphism of the inducible nitric oxide synthase gene in celiac disease.
pubmed:affiliation
Instituto de Parasitologia y Biomedicina Lopez-Neyra, CSIC, Granada, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't