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pubmed:abstractText |
Previous studies have shown that the short arm of chromosome 5 (5p) exhibit frequent genetic changes in invasive cervical carcinoma (CC), and that these changes arise early during the carcinogenesis, in precancerous lesions. These data therefore suggest that loss of candidate tumor suppressor genes located on 5p is associated with the development of CC. However, the precise location of 5p deletions is not known.
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pubmed:affiliation |
Department of Pathology, College of Physicians & Surgeons of Columbia University, 630 West 168th Street, New York, 10032, USA. harias59@yahoo.com
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