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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
17
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pubmed:dateCreated |
2002-10-22
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pubmed:abstractText |
Rheumatoid arthritis (RA) is associated with accelerated atherosclerosis and increased cardiovascular morbidity and mortality. Striking similarities exist in the inflammatory and immunologic response in RA and atherosclerosis. Indeed, adhesion molecules and cytokines, tumor necrosis factor (TNF)-alpha in particular, are key mediators of joint inflammation and of vascular dysfunction and progression of atherosclerotic vascular disease. Hence, the aim of the present study was to assess the effect of chronic antiinflammatory treatment with the anti-TNF-alpha antibody infliximab on disease activity and endothelial function in patients with active RA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:BéchirMarkusM,
pubmed-author:ChenevardRémyR,
pubmed-author:DistlerOliverO,
pubmed-author:EnseleitFrankF,
pubmed-author:ForsterAdrianA,
pubmed-author:GayRenate ERE,
pubmed-author:GaySteffenS,
pubmed-author:HürlimannDavidD,
pubmed-author:LüscherThomas FTF,
pubmed-author:MichelBeat ABA,
pubmed-author:NeidhartMichelM,
pubmed-author:NollGeorgG,
pubmed-author:RuschitzkaFrankF,
pubmed-author:SpiekerLukas ELE
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pubmed:issnType |
Electronic
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pubmed:day |
22
|
|
pubmed:volume |
106
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2184-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12390945-Antibodies, Monoclonal,
pubmed-meshheading:12390945-Antirheumatic Agents,
pubmed-meshheading:12390945-Arthritis, Rheumatoid,
pubmed-meshheading:12390945-Brachial Artery,
pubmed-meshheading:12390945-C-Reactive Protein,
pubmed-meshheading:12390945-Endothelium, Vascular,
pubmed-meshheading:12390945-Female,
pubmed-meshheading:12390945-Humans,
pubmed-meshheading:12390945-Male,
pubmed-meshheading:12390945-Middle Aged,
pubmed-meshheading:12390945-Tumor Necrosis Factor-alpha,
pubmed-meshheading:12390945-Vasodilation
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pubmed:year |
2002
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|
pubmed:articleTitle |
Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis.
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pubmed:affiliation |
Cardiology Department, University Hospital, Zürich, Switzerland.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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