The source of new cells in the normal adult liver has been controversial. Some investigators have hypothesized the streaming liver model. On the other hand, others reject this hypothesis. We examined hepatic cell kinetics by a special labeling method with [3H]thymidine.
Division of Gene Therapy, Intractable Disease Reseach Center, Tokyo Medical University, 6-1-1, Shinjuku, Shinjuku-ku, Tokyo, Japan. magami@tokyo-med.ac.jp