| pubmed-article:12381666 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0025260 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0018866 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0043189 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C1655731 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0728826 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0013138 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C1160285 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C1709061 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:12381666 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:12381666 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:12381666 | pubmed:dateCreated | 2002-10-16 | lld:pubmed |
| pubmed-article:12381666 | pubmed:abstractText | In Drosophila, the Trithorax-group (trxG) and Polycomb-group (PcG) proteins interact with chromosomal elements, termed Cellular Memory Modules (CMMs). By modifying chromatin, this ensures a stable heritable maintenance of the transcriptional state of developmental regulators, like the homeotic genes, that is defined embryonically. We asked whether such CMMs could also control expression of genes involved in patterning imaginal discs during larval development. Our results demonstrate that expression of the hedgehog gene, once activated, is maintained by a CMM. In addition, our experiments indicate that the switching of such CMMs to an active state during larval stages, in contrast to embryonic stages, may require specific trans-activators. Our results suggest that the patterning of cells in particular developmental fields in the imaginal discs does not only rely on external cues from morphogens, but also depends on the previous history of the cells, as the control by CMMs ensures a preformatted gene expression pattern. | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12381666 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12381666 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12381666 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:12381666 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:12381666 | pubmed:author | pubmed-author:MaurangeCédri... | lld:pubmed |
| pubmed-article:12381666 | pubmed:author | pubmed-author:ParoRenatoR | lld:pubmed |
| pubmed-article:12381666 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12381666 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:12381666 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:12381666 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12381666 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12381666 | pubmed:pagination | 2672-83 | lld:pubmed |
| pubmed-article:12381666 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
