High-intensity transient signals (HITS) are frequently detected by transcranial Doppler (TCD) ultrasound in patients with mechanical prosthetic heart valves (PHVs), but published data about their clinical relevance are controversial. This study was undertaken to determine the clinical relevance of HITS in patients with mechanical PHVs.
Stroke Research Unit, Division of Neurology, Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Canada. nadareishviliz@ninds.nih.gov
