|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0016360,
umls-concept:C0030705,
umls-concept:C0036525,
umls-concept:C0040808,
umls-concept:C0087111,
umls-concept:C0231174,
umls-concept:C0282460,
umls-concept:C0441655,
umls-concept:C0453882,
umls-concept:C1522484,
umls-concept:C1527249,
umls-concept:C2698651
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2002-10-14
|
|
pubmed:abstractText |
We have investigated the efficacy, safety and quality of life profiles of three therapeutic combinations [irinotecan + leucovorin (LV)/5-fluorouracil (5-FU), oxaliplatin + LV/5-FU and irinotecan +oxaliplatin] in patients with metastatic colorectal cancer after failure of a 5-FU-based regimen, or whose disease had progressed within 6 months of the end of treatment.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0923-7534
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
13
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1558-67
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:12377643-Adult,
pubmed-meshheading:12377643-Aged,
pubmed-meshheading:12377643-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12377643-Camptothecin,
pubmed-meshheading:12377643-Colorectal Neoplasms,
pubmed-meshheading:12377643-Disease Progression,
pubmed-meshheading:12377643-Drug Resistance, Neoplasm,
pubmed-meshheading:12377643-Female,
pubmed-meshheading:12377643-Fluorouracil,
pubmed-meshheading:12377643-Humans,
pubmed-meshheading:12377643-Infusions, Intravenous,
pubmed-meshheading:12377643-Injections, Intravenous,
pubmed-meshheading:12377643-Leucovorin,
pubmed-meshheading:12377643-Male,
pubmed-meshheading:12377643-Middle Aged,
pubmed-meshheading:12377643-Neoplasm Metastasis,
pubmed-meshheading:12377643-Neutropenia,
pubmed-meshheading:12377643-Organoplatinum Compounds,
pubmed-meshheading:12377643-Quality of Life,
pubmed-meshheading:12377643-Survival,
pubmed-meshheading:12377643-Treatment Outcome
|
|
pubmed:year |
2002
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|
pubmed:articleTitle |
Antitumour activity of three second-line treatment combinations in patients with metastatic colorectal cancer after optimal 5-FU regimen failure: a randomised, multicentre phase II study.
|
|
pubmed:affiliation |
Hôpital Ambroise Paré, Boulogne, France. philippe.rougier@apr.ap-hop-paris.fr
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
|
