Source:http://linkedlifedata.com/resource/pubmed/id/12376201
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
15
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pubmed:dateCreated |
2002-10-11
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pubmed:abstractText |
The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) trial is a randomised, double-blind, double-dummy trial, evaluating anastrozole alone or in combination with tamoxifen compared with tamoxifen alone, as a 5-year adjuvant treatment for postmenopausal patients with early breast cancer. The rapid rate of recruitment into this trial was a major achievement, as frequently encountered differences between projected and actual recruitment rates can threaten the successful completion of clinical trials. A questionnaire designed in order to highlight possible factors influencing the success of patient recruitment was completed by 62% of the ATAC trialists. This included 11 statements rated for their level of importance on a three-point scale. The top three motives for recruiting patients were: (1) the attractive scientific rationale of the trial (84%); (2) a design that was easy to explain to patients (79%); and (3) a pragmatic trial design in line with standard practice (76%). A new questionnaire will solicit opinion from the participating patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0959-8049
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1984-6
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:12376201-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12376201-Breast Neoplasms,
pubmed-meshheading:12376201-Chemotherapy, Adjuvant,
pubmed-meshheading:12376201-Double-Blind Method,
pubmed-meshheading:12376201-Female,
pubmed-meshheading:12376201-Humans,
pubmed-meshheading:12376201-Nitriles,
pubmed-meshheading:12376201-Patient Selection,
pubmed-meshheading:12376201-Postmenopause,
pubmed-meshheading:12376201-Questionnaires,
pubmed-meshheading:12376201-Tamoxifen,
pubmed-meshheading:12376201-Triazoles
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pubmed:year |
2002
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pubmed:articleTitle |
The ATAC (Arimidex, Tamoxifen, Alone or in Combination) adjuvant breast cancer trial in postmenopausal patients: factors influencing the success of patient recruitment.
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pubmed:affiliation |
The Portland Hospital, First Floor, 212-214 Great Portland Street, London W1W 5QN, UK. m.baum@ctc.ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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